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Projet.Rmd
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@ -52,12 +52,12 @@ levels(T$ExpT1)
# Contenu du jeu de données : # Contenu du jeu de données :
Le jeu de données contient 3 variables qualitatives nominales représentant l'expression du gêne g dont les modalités sont {"sur","sous","non"}. Chaque variable correspond respectivement à la différence d'expression du gêne mesurée à la 6ème heure lors du traitement T appartient à {T1,T2,T3} en moyenne, sur les réplicats {R1,R2}. Le jeu de données contient 3 variables qualitatives nominales représentant l'expression du gêne g dont les modalités sont {"sur","sous","non"}. Chaque variable correspond respectivement à la différence d'expression du gêne mesurée à la 6ème heure lors du traitement T appartenant à {T1,T2,T3} en moyenne, sur les réplicats {R1,R2}.
3x6 + 3x6 = 36 variables quantitatives continues représentant les effets des traitements sur l'expression des gênes T1 T2 et T3 à 1h,2h,3h,4h,5h,6h après l'administration pour les replicats {R1,R2}, par rapport à leur expression à T=0 ( sans traitement). Ce jeu de données contient des relevés sur 542 individus, ici des gênes. 3x6 + 3x6 = 36 variables quantitatives continues représentant les effets des traitements T1 T2 et T3 sur l'expression des gênes à 1h,2h,3h,4h,5h,6h après l'administration pour les replicats {R1,R2}, par rapport à leur expression à T=0 ( sans traitement). Ce jeu de données contient des relevés sur 542 individus, ici des gênes.
# Analyse unidimentionnelle : # Analyse unidimensionnelle :
## Expression des gênes lors des traitements T1,T2 et T3 ## Expression des gênes lors des traitements T1,T2 et T3
@ -785,14 +785,12 @@ Le cluster 1 correspond aux gènes sur-exprimés et le cluster 3 aux gènes sous
## Clustering des gènes à partir des variables ExpT1, ExpT2 et ExpT3.
Comme ce sont des données qualitatives, on doit utiliser des méthodes alternatives de clustering comme les kmodes ou les kmeans mais sur les coordonnées de points projetés dans le plan d'une ACM
## Approfondissement de L'ACP avec un clustering de 7 classes ## Approfondissement de L'ACP avec un clustering de 7 classes
Sur la figure \ref{fig:intra2}, on peut aussi remarquer un coude aux alentours de 7 classes, nous avons donc décidé de compléter notre analyse par un clustering à 7 classes dont on peut voir la projection dans le plan factoriel sur la Figure \ref{fig:clust3} et Figure \ref{fig:evol2} l'évolution de l'expression moyenne des gènes par cluster, en fonction du temps. Sur la figure \ref{fig:sil2}, sur le graphe de l'inertie intraclasse on peut aussi remarquer un coude aux alentours de 7 classes, nous avons donc décidé de compléter notre analyse par un clustering à 7 classes dont on peut voir la projection dans le plan factoriel sur la Figure \ref{fig:clust3} et Figure \ref{fig:evol2} l'évolution de l'expression moyenne des gènes par cluster, en fonction du temps.

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